Your participation in Clinical research can make a difference

Help shape the future of diabetes care in Grampian

Take part in research studies to improve treatments, technology, and support for people living with diabetes.

The Grampian Diabetes Clinical research unit is based at the JJR Macleod Centre at Aberdeen Royal Infirmary. The unit is involved in supporting the delivery of clinical research to improve the lives of people with diabetes. 

 

Research Studies

We run studies to improve how diabetes is treated and managed.

New Treatments

We test new medicines, devices, and ways of delivering care.

Better Care

Our work helps improve services for people across NHS Grampian.

New Studies

PREVENT-HF Study
Help protect heart health in Type 2 diabetes

Researchers are studying whether a new treatment can reduce the risk of heart failure in people with Type 2 diabetes and cardiovascular disease.

      –  Age 40+
      –  Type 2 diabetes
      –  High blood pressure
      –  Heart or blood vessel disease

Learn More and Check Eligibility? >

ENITH2 Study
Weight Management in Type 2 Diabetes

Researchers are evaluating a new investigational medication (enicepatide) for people living with overweight or obesity and Type 2 diabetes.

      –   Age 18+ 

      –    Type 2 diabetes

      –    BMI 27 kg/m² or above

Am I Eligible? >

BARICADE Study
Recently diagnosed with Type 1 diabetes?

Researchers are evaluating whether a new treatment (baricitinib) can help preserve the body’s remaining insulin-producing cells following a diagnosis of Type 1 diabetes.

      –   Age 1 to 35 years 

      –    Type 1 diabetes diagnosed within the last 100 days

  Am I Eligible? >

ADDRESS-2
Recently diagnosed with Type 1 diabetes?

A research programme helping people newly diagnosed with Type 1 diabetes learn about and participate in research studies. Based on eligibility, participants may be informed about future clinical trials and observational studies.

      –   Recent Type 1 diabetes diagnosis

  Am I Eligible? >

Principal Investigator – Prof Sam Philip
Sub-Investigators – Dr Anna Smart , Dr Mathew Suresh

Research Nurses:

Siby Joseph
Julie Toye
Fiona Mckinstry

Research Assistant:
Shukurat Atunshe

Research Administrator: Pamela Souter

NHS Grampian  research and Development

David Anderson Building
Aberdeen, AB25 2ZP

Health Sciences Building,
Aberdeen Royal Infirmary,
Foresterhill, Aberdeen, AB25 2ZD

Tel: 01224 558125
gram.diabetesresearch@nhs.scot

Cost‐effectiveness of fenofibrate versus standard care for reducing the progression of diabetic retinopathy: An economic evaluation based on data from the LENS trial
G Scotland, M Tsehaye, C Styles, J Logue, E Sammons, M Zayed, …
Diabetic Medicine, e70098
 2025
Adrenocortical carcinoma classified as benign: the limitations of washout values
PS Yap, S Philip, AJ Graveling, D McAteer, S Aspinall, P Abraham
Endocrinology, Diabetes & Metabolism Case Reports 2025 (2)
 2025
Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes
MA Bantounou, P Sardellis, J Plascevic, R Awaes‐Mahmood, …
ESC Heart Failure 12 (2), 968-979
52025
Drug Exposure As a Predictor in Diabetic Retinopathy Risk Prediction Models—A Systematic Review and Meta-Analysis
MA Bantounou, TAK Nahar, J Plascevic, N Kumar, M Nath, PK Myint, …
American Journal of Ophthalmology 268, 29-44
12024
Morning exercise and pre‐breakfast metformin interact to reduce glycaemia in people with type 2 diabetes: a randomized crossover trial
BJP Carrillo, E Cope, S Gurel, A Traslosheros, A Kenny, O Michot‐Duval, …
The Journal of physiology 602 (23), 6491-6506
92024
AUDIT OF DIABETES CARE PROCESSES IN PATIENTS WITH DIABETES ATTENDING MEDICAL RETINA (MR) CLINICS
DJ Maclean, S Philip, C Santiago
EYE 38, 125-125
 2024
iDiabetes platform—enhanced phenotyping of patients with diabetes for precision diagnosis, prognosis and treatment: study protocol for a cluster-randomised controlled study in …
YY Lin, D Leith, M Abbott, R Barrett, S Bell, TJ Croudace, S Cunningham, …
BMJ open 14 (11), e086594
22024
The association between type 2 diabetes mellitus and Parkinson’s disease; a systematic review and meta-analysis
MA Bantounou, K Shoaib, A Mazzoleni, H Modalavalasa, N Kumar, …
Brain Disorders 15, 100158
72024
Design, recruitment and baseline characteristics of the LENS trial
LENS Collaborative Group, D Preiss, J Logue, E Sammons, M Zayed, …
Diabetic Medicine 41 (9), e15310
52024
At-home multispectral imager for the monitoring of blood oxygenation in people at risk of diabetic foot ulcers
K Shand, J Thomson, S Philip, J Boers, C Robertson, ME Giardini
Clinical Biophotonics III 13009, 17-23
 2024
Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes
AM Mezincescu, A Rudd, L Cheyne, G Horgan, S Philip, D Cameron, …
Nature communications 15 (1), 3690
42024
Ongoing burden and recent trends in severe hospitalised hypoglycaemia events in people with type 1 and type 2 diabetes in Scotland: A nationwide cohort study 2016–2022
W Berthon, SJ McGurnaghan, LAK Blackbourn, J Mellor, FW Gibb, …
Diabetes Research and Clinical Practice 210, 111642
42024
Creating a SNOMED CT reference set for common endocrine disorders based on routine clinic correspondence
SHA Yap, S Philip, AJ Graveling, P Abraham, D Downs
Clinical Endocrinology 100 (4), 343-349
12024
Effect of the dual sodium‐glucose co‐transporter‐1 and‐2 inhibitor sotagliflozin on renal outcomes in type 1 diabetes and type 2 diabetes: A systematic review and meta‐analysis …
MA Bantounou, P Sardellis, R Thuemmler, D Black Boada, J Kaczmarek, …
Diabetes, Obesity and Metabolism 26 (2), 710-720
12024
Mild autonomous cortisol secretion in patients with adrenal incidentalomas-how common and what is the prevalence of co-morbidities?
PS Yap, R Paterson, S Philip, AJ Graveling, P Abraham
Endocrine Abstracts 94
 2023
Myeloid PTP1B deficiency protects against atherosclerosis by improving cholesterol homeostasis through an AMPK-dependent mechanism
H Oliver, D Ruta, D Thompson, S Kamli-Salino, S Philip, HM Wilson, …
Journal of translational medicine 21 (1), 715
42023
Smartphone-based retinal imager for self-monitoring of diabetic retinopathy
K Shand, J Thomson, S Philip, J Boers, ME Giardini
Euretina
 2023
Compound scaling encoder-decoder (CoSED) network for diabetic retinopathy related bio-marker detection
D Yi, P Baltov, Y Hua, S Philip, PK Sharma
IEEE journal of biomedical and health informatics 28 (4), 1959-1970
62023
Morning exercise and pre-breakfast metformin interact to reduce glycaemia in people with Type 2 Diabetes: a randomized crossover trial
PC BJ, E Cope, S Gurel, A Traslosheros, A Kenny, N Mody, M Delibegovic, …
 
 2023
Morning exercise reduces glycaemia in people with type 2 diabetes also being prescribed metformin
BM Gabriel, BP Carrillo, O Duval, E Cope, S Gurel, A Kenny, S Philip, …
DIABETOLOGIA 66 (SUPPL 1), S249-S249
 2023
Type 1 diabetes incidence in Scotland between 2006 and 2019
I Thomson, N Anderson, L Bath, S Kiff, C Patterson, S Philip, N Waugh, …
Diabetic Medicine 40 (8), e15069
22023
Kidney and cardiovascular effects of canagliflozin according to age and sex: a post hoc analysis of the CREDENCE randomized clinical trial
TW Yi, B Smyth, GL Di Tanna, C Arnott, K Cardoza, A Kang, C Pollock, …
American Journal of Kidney Diseases 82 (1), 84-96. e1
192023
Evaluating quality of care in young people with type 2 diabetes (18-25) across Scotland using Realtime SCI-diabetes dashboard
AD White, R Rashid, RJ Wright, B Kennon, S Philip
DIABETIC MEDICINE 40
 2023
Diabetes specialist nurse follow-up for people living with diabetes who are experiencing significant hypoglycaemic events: Learning from a pilot with the Scottish ambulance service
J McGillivray, E Hall, K Jenson, A Parker, R O’Donnell, E Moffat, S Philip, …
DIABETIC MEDICINE 40
 2023
Insulin Resistance in Type 2 Diabetes is Moderated by Saturated Fatty Acids
AM Mezincescu, A Rudd, L Cheyne, G Horgan, S Philip, D Cameron, …
Circulation 146 (Suppl_1), A10408-A10408
 2022
Cohort profile: the Scottish Diabetes Research Network national diabetes cohort–a population-based cohort of people with diabetes in Scotland
SJ McGurnaghan, LAK Blackbourn, TM Caparrotta, J Mellor, A Barnett, …
BMJ open 12 (10), e063046
212022
Adherence to a remotely monitored exercise intervention using wearable technology
BJ Carrillo, S Philip, F Thies, D Blana, B Gabriel
ACTA PHYSIOLOGICA 236, 729-729
 2022
Automated data extraction of structured clinical correspondence with SNOMED coding to assess regional epidemiology of common pituitary conditions
AYS Hao, A Graveling, P Abraham, S Philip
Endocrine Abstracts 81
 2022
User-centered design of a novel risk prediction behavior change tool augmented with an artificial intelligence engine (MyDiabetesIQ): a sociotechnical systems approach
C Shields, SG Cunningham, DJ Wake, E Fioratou, D Brodie, S Philip, …
JMIR human factors 9 (1), e29973
162022
Foot ulcer and risk of lower limb amputation or death in people with diabetes: a national population-based retrospective cohort study
RC Chamberlain, K Fleetwood, SH Wild, HM Colhoun, RS Lindsay, …
Diabetes Care 45 (1), 83-91
882022
Flash monitor initiation is associated with improvements in HbA1c levels and DKA rates among people with type 1 diabetes in Scotland: a retrospective nationwide …
A Jeyam, FW Gibb, JA McKnight, JE O’Reilly, TM Caparrotta, A Höhn, …
Diabetologia 65 (1), 159-172
272022
Adrenal Incidentaloma Pathway-A four-year experience at a teaching hospital
R Rajan, SGKM Chandy, P Radhakrishnan, R Paterson, S Aspinall, …
Endocrine Abstracts 77
12021
Rising rates and widening socioeconomic disparities in diabetic ketoacidosis in type 1 diabetes in Scotland: a nationwide retrospective cohort observational study
JE O’Reilly, A Jeyam, TM Caparrotta, J Mellor, A Hohn, PM McKeigue, …
Diabetes Care 44 (9), 2010-2017
222021
Frontline community health care workers’ intervention for diabetes management in resource limited settings: a qualitative study on perspectives of key stakeholders
A Poobalan, E Whiteley, B Balsubramanya, S Philip, P Jebaraj, BV Balaji, …
Journal of Global Health Reports
12021
Marked improvements in glycaemic outcomes following insulin pump therapy initiation in people with type 1 diabetes: a nationwide observational study in Scotland
A Jeyam, FW Gibb, JA McKnight, B Kennon, JE O’Reilly, TM Caparrotta, …
Diabetologia 64 (6), 1320-1331
332021
Use of C-methionine PET-CT scanning to guide management of acromegaly following primary therapy–A pragmatic prioritisation strategy to achieve maximal cost effectiveness
R Rajan, D Bhatt, S Philip, AJ Graveling, M Kamel, S Olson, F Mckiddie, …
Endocrine Abstracts 73
 2021
Improved response to somatostatin analogue (SSA) therapy in acromegaly following treatment pause
R Rajan, D Bhatt, S Philip, AJ Graveling, W Bashari, M Gurnell, …
Endocrine Abstracts 73
 2021
Public Health Scotland COVID-19 Health Protection Study Group; Scottish Diabetes Research Network Epidemiology Group. Risks of and risk factors for COVID-19 disease in people …
SJ McGurnaghan, A Weir, J Bishop, S Kennedy, LAK Blackbourn, …
Lancet Diabetes Endocrinol 9 (2), 82-93
552021
Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland
SJ McGurnaghan, A Weir, J Bishop, S Kennedy, LAK Blackbourn, …
The lancet Diabetes & endocrinology 9 (2), 82-93